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The cumulative impact of these chemicals over time can lead to chronic lung diseases and significantly reduce life expectancy

Besides nicotine, e-cigarettes contain other harmful and carcinogenic chemicals such as propylene glycol, flavoring agents such as diacetyl (which has been linked to lung disease), heavy metals, and other volatile compounds

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Based on animal experiments and human cell studies, a research group led by Alex Carll, professor of physiology at the University of Louisville School of Medicine in the United States, has for the first time identified that synthetic cooling additives commonly added to e-cigarettes can induce cardiac arrhythmias

Identifying these diverse risk factors is essential for understanding regional variations in COPD prevalence and for assessing the potential role of emerging exposures such as e-cigarette use